OMICS Lead – Lab Manager II

The University of Pittsburgh is establishing a state-of-the-art, multi-omics facility to support research and clinical translational programs in multiple OMICS disciplines including genomic sequencing, metagenomics, and RNA sequencing. We are seeking a highly motivated senior technician with experience in these areas and demonstrated team skills. 1. Independently perform clinical testing in accordance with established SOPs. Process all clinical, QC and PT specimens through clinical workflow. 2 Demonstrate high-level problem-solving skills and analytical abilities to successfully perform laboratory testing. 3 Accurately record relevant data and values in case folders and internal databases. Perform high-volume sample triage, accessioning, and barcoding according to CAP/CLIA and institutional SOPs. Ensure complete and accurate logging of sample receipt, aliquoting, and storage in the LIMS to maintain traceability across all omics workflows. 4 Maintain proficiency in LIMS for comprehensive sample tracking and workflow documentation. Use barcode scanning to monitor progress and link sample metadata to assay results across genomic, proteomic, and metabolomic pipelines. 5 Maintain expertise in or knowledge of molecular biology techniques, including but not limited to: nucleic acid isolation, nucleic acid quantitation, PCR/RT-PCR/qPCR, Sanger sequencing, LOH, methylation analysis, MassARRAY MALDI-TOF, next-generation sequencing, etc. 6 Independently operate automated and/or liquid handling machines for clinical testing, including high-throughput sample preparation and assay setup. 7 Accurately and precisely analyze molecular assay results for final interpretation by medical staff. 8 Process samples meticulously to avoid cross-contamination. 9 Meet established turn-around-time deadlines for clinical testing. 10 Operate, perform routine maintenance on, and calibrate all laboratory equipment as required. 11 Identify problems with instrumentation, methodology, specimens, and/or supplies and follow-up according to established protocols. 12 Identify critical, abnormal and/or unacceptable results and follow-up according to established protocol. 13 Document all corrective action and follow-up with lead and/or supervisor. 14 Effectively communicate with other laboratory members including lab leadership. 15 Maintain track of technical and professional development, including but not limited to attendance at seminars/webinars and participation in educational programs and activities. 16 Adhere to established laboratory and hospital policies and good clinical laboratory practice in areas of procedures, quality control, quality assurance and safety and compliance. 17 Assist in research projects, new assay development and/or document control review as requested. 18 Train new lab members. 19 Maintain supply inventory and order new supplies when needed. 20 Help with instrument maintenance / PM. 21 Demonstrate excellent organizational skills and time management to process large batches of samples efficiently while maintaining accuracy and compliance under strict turnaround-time requirements. 22 Contribute to cross-platform QA/QC efforts, ensuring harmonization of standards across genomics, proteomics.

Manages day-to-day laboratory operations while ensuring compliance with safety regulations and best practices. Works with, adapts, and installs scientific equipment in research laboratories. Develops and collaborates on routine projects and procedures. Manages inventory and equipment and performs budget functions.

The University of Pittsburgh is establishing a state-of-the-art, multi-omics facility to support research and clinical translational programs in multiple OMICS disciplines including genomic sequencing, metagenomics, and RNA sequencing. We are seeking a highly motivated senior technician with experience in these areas and demonstrated team skills. 1. Independently perform clinical testing in accordance with established SOPs. Process all clinical, QC and PT specimens through clinical workflow. 2 Demonstrate high-level problem-solving skills and analytical abilities to successfully perform laboratory testing. 3 Accurately record relevant data and values in case folders and internal databases. Perform high-volume sample triage, accessioning, and barcoding according to CAP/CLIA and institutional SOPs. Ensure complete and accurate logging of sample receipt, aliquoting, and storage in the LIMS to maintain traceability across all omics workflows. 4 Maintain proficiency in LIMS for comprehensive sample tracking and workflow documentation. Use barcode scanning to monitor progress and link sample metadata to assay results across genomic, proteomic, and metabolomic pipelines. 5 Maintain expertise in or knowledge of molecular biology techniques, including but not limited to: nucleic acid isolation, nucleic acid quantitation, PCR/RT-PCR/qPCR, Sanger sequencing, LOH, methylation analysis, MassARRAY MALDI-TOF, next-generation sequencing, etc. 6 Independently operate automated and/or liquid handling machines for clinical testing, including high-throughput sample preparation and assay setup. 7 Accurately and precisely analyze molecular assay results for final interpretation by medical staff. 8 Process samples meticulously to avoid cross-contamination. 9 Meet established turn-around-time deadlines for clinical testing. 10 Operate, perform routine maintenance on, and calibrate all laboratory equipment as required. 11 Identify problems with instrumentation, methodology, specimens, and/or supplies and follow-up according to established protocols. 12 Identify critical, abnormal and/or unacceptable results and follow-up according to established protocol. 13 Document all corrective action and follow-up with lead and/or supervisor. 14 Effectively communicate with other laboratory members including lab leadership. 15 Maintain track of technical and professional development, including but not limited to attendance at seminars/webinars and participation in educational programs and activities. 16 Adhere to established laboratory and hospital policies and good clinical laboratory practice in areas of procedures, quality control, quality assurance and safety and compliance. 17 Assist in research projects, new assay development and/or document control review as requested. 18 Train new lab members. 19 Maintain supply inventory and order new supplies when needed. 20 Help with instrument maintenance / PM. 21 Demonstrate excellent organizational skills and time management to process large batches of samples efficiently while maintaining accuracy and compliance under strict turnaround-time requirements. 22 Contribute to cross-platform QA/QC efforts, ensuring harmonization of standards across genomics, proteomics.

Sitting and standing for long periods, walking around campus to attend meetings. Bending and lifting to put away supplies. Lifting to 30 pounds. Reading small print on tubes, vials and documents. Working in a lab under standard lighting.